The rune slot system lets you choose how you play your class

Diablo 3’s rune system looks cool. Basically every class has rune slots that allow you to add effects to your class abilities. An example would be the witch doctors flaming skull. With the multi rune the skull bounces and destroys everything in it’s path. This allows you to customize your class and play it in the manner that you want it to be played.
Examples after the jump:
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